Welcome to the Biophysics Group at CMU!

Biophysics is an exciting interdisciplinary frontier in physics. It applies tools and techniques of physics to understand how biological systems work, from the scales of single molecules to an entire living organism—and beyond. At the same time, biological phenomena offer us physicists unique opportunities to learn new physics on complex, non-equilibrium systems.

The Biophysics Group at Carnegie Mellon combines theory, experiments and computational modelling to investigate the fundamental principles that govern the structure, mechanics and dynamic behavior of living systems across different levels of biological organization and complexities.

For more details on our ongoing research activities, please have a look here.


Theory and Simulations


Theory and Simulation


Single-Molecule Biophysics

 Heinrich and

 Lösche Group

Molecular Events in Cell Signaling


Interfacial Science


Experiment and Theory



Research Highlights

“Uncovering a membrane-distal conformation of KRAS available to recruit RAF to the plasma membrane.”, F. Heinrich, M. Lösche and collaborators

PNAS 117, 24258 (2020)       (Commentary)


“Spontaneous curvature, differential stress, and bending modulus of asymmetric lipid membranes”, A. Hossein and M. Deserno.

Biophys. J. 118, 624–642 (2020).


“Surface-to-volume scaling and aspect ratio preservation in rod-shaped bacteria”, N. Ojkic, D. Serbanescu and S. Banerjee.

eLife 8, e47033 (2019).


Flow regime transitions and effects on solute transport in surfactant-driven Marangoni flows“, S.V. Iasella, N. Sun, X. Zhang, T.E. Corcoran, S. Garoff, T.M. Przybycien, R.D. Tilton.

J. Colloid Interface Sci. 553, 136–147 (2019).

Synergistic biophysical techniques reveal structural mechanisms of engineered cationic antimicrobial peptides in lipid model membranes”, F. Heinrich, A. Salyapongse, A. Kumagai, F.G. Dupuy, K. Shukla, A. Penk, D. Huster, R.K. Ernst, A. Pavlova, J.C. Gumbart, B. Deslouches,Y.P. Di, and S. Tristram-Nagle.

 Chem. Eur. J. 26, 6247–6256 (2020).